Ostarine (MK-2866) – For Muscle Definition and Recovery | 10mg, 60 Caps

Ostarine (MK-2866): The Gold Standard SARM for Muscle Retention & Growth

DISCLAIMER: For research purposes only. Not for human or veterinary use.

Ostarine, also known as MK-2866 or Enobosarm, is a premier Selective Androgen Receptor Modulator (SARM). Originally developed to combat muscle wasting (cachexia) and osteoporosis, it has become one of the most widely researched compounds in the fitness community. Ostarine provides significant anabolic activity without the harsh androgenic side effects associated with traditional anabolic steroids.

Chemical & Biological Properties

• IUPAC Name: (2S)-3-(4-cyanophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide
• CAS Number: 841205-47-8
• Molecular Formula: C₁₉H₁₈F₃N₃O₃
• Molar Mass: 389.33 g/mol
• Binding Affinity: High selectivity with a Ki of 3.8 nM for the androgen receptor.
• Elimination Half-Life: Approximately 24 hours, supporting a stable once-daily dosing protocol.
• Solubility: Soluble in DMSO and ethanol; poorly soluble in water.

Mechanism of Action

Ostarine selectively binds to androgen receptors specifically in muscle and bone tissues. This targeted stimulation triggers anabolic activity and protein synthesis while minimizing androgenic impact on secondary organs like the prostate. Crucially, MK-2866 does not aromatize into estrogen, significantly reducing the risk of gynecomastia and water retention.

Potential Research Benefits

• Lean Muscle Growth: Effectively promotes muscle hypertrophy and raw strength gains.
• Muscle Preservation: The most effective SARM for protecting muscle mass during aggressive caloric deficits.
• Bone & Joint Support: Enhances bone mineral density and may aid in the recovery of tendons and ligaments.
• Body Recomposition: Facilitates simultaneous fat loss and muscle gain due to its nutrient partitioning effects.
• Oral Bioavailability: Highly effective when administered orally, eliminating the need for injections.

Recommended Cycling Protocols

Ostarine is highly versatile and can be used for various research goals depending on the dosage and cycle length.

1. Standard Cycle Lengths

• Beginner: 6–8 weeks at 10–15 mg/day.
• Intermediate: 8–10 weeks at 15–20 mg/day.
• Advanced: 10–12 weeks at 20–25 mg/day (Increased risk of suppression at these levels).

2. Goal-Specific Research Stacks

• Bulking: 20 mg/day for 8 weeks. To maximize gains, maintain a caloric surplus with high protein intake.
• Cutting: 10 mg/day for 8 weeks. Commonly paired with Cardarine (GW-501516) at 15 mg/day to shred fat while preserving lean tissue.
• Body Recomposition: 15 mg/day for 8 weeks. Often combined with Cardarine to improve endurance and metabolic efficiency.

Side Effects & Detection Time

While Ostarine is considered one of the mildest SARMs, research subjects should be monitored for:

• Testosterone Suppression: Mild to moderate suppression can occur, particularly at doses above 15 mg or cycles longer than 8 weeks.
• Liver Enzymes: Potential for slight elevations with prolonged or high-dose use.
• Detection (Urine): Detectable for approximately 14 days after a single 30 mg dose.
• Detection (Blood): Traceable for 9–11 days depending on metabolism and dosage.

Post-Cycle Therapy (PCT)

Is PCT required? For cycles over 8 weeks or dosages exceeding 15 mg/day, a 4-week PCT is recommended. Common agents include Nolvadex or Enclomiphene (6 mg every other day) to ensure natural testosterone levels recover promptly.

Product Specification: “OSTA”

Serving Size: 1 Capsule
Servings Per Container: 60

* Daily Value (DV) not established.